A rep for the longtime daytime host, 67, confirmed to Entertainment Weekly on Monday that Goldberg had been feeling ill prior to the show and tests later confirmed she had contracted the virus.
Joy Behar, who also moderates discussions on the show, was absent as well as she was already scheduled to be off this week, the outlet reports.
This is the second time that Goldberg has been missing from the show due to COVID.
Goldberg tested positive in January and missed a few episodes after the Christmas holiday break.
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She told her fellow co-hosts about her diagnosis via livestream, saying she started experiencing mild symptoms over the break and had taken some time off the show to rest.
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“It was a shock, because I’m triple vaxxed, I haven’t been anywhere, I haven’t done anything,” Goldberg said.
“It’s one of those things where you think, I’ve done everything I was supposed to do… Yeah, it doesn’t stop omicron.”